Program
Tuesday, December 11, 2012
Satellite Symposia - Krehl Klinik Auditorium (INF 410)
12:00 - 2:00 pm
2:00 - 2:30 pm
Coffee Break
2:30 - 4:00 pm
Next-Generation Sequencing
(Org. Stefan Wiemann and Bernd Timmermann)
Download Program Satellite Symposium NGS
(Org. Stefan Wiemann and Bernd Timmermann)
Download Program Satellite Symposium NGS
4:00 - 4:30 pm
Coffee Break
Welcome- DKFZ Communication Center
4.30– 5.00 pm
Wolfgang Wurst, Helmholtz Zentrum Munich, Germany, Speaker Project Committee of NGFN-Plus / NGFN-Transfer in the Program of Medical Genome Research
N.N., Federal Minstry of Education and Research, Germany
Christof von Kalle, National Center for Tumor Diseases (NCT)/ German Cancer Research Center (DKFZ), Heidelberg, Germany
N.N., Federal Minstry of Education and Research, Germany
Christof von Kalle, National Center for Tumor Diseases (NCT)/ German Cancer Research Center (DKFZ), Heidelberg, Germany
Symposium I: International Projects in the Program of Medical Genome Research
5.00 – 5.30 pm
International Cancer Genome Consortium (ICGC)
Michael Taylor, The Hospital for Sick Children, Toronto, Canada
Michael Taylor, The Hospital for Sick Children, Toronto, Canada
5.30 – 6.00 pm
International Cancer Genome Consortium (ICGC)
Peter Lichter, German Cancer Research Center, Heidelberg, Germany
Novel findings in pediatric brain tumors revealed by high resolution genome, methylome and transcriptome analyses
Peter Lichter, German Cancer Research Center, Heidelberg, Germany
Novel findings in pediatric brain tumors revealed by high resolution genome, methylome and transcriptome analyses
6.00 – 6.30 pm
International Cancer Genome Consortium (ICGC)
Matthew Meyerson, Dana Farber Cancer Institute, Boston, USA
Genome Alterations in Human Lung Cancers
Matthew Meyerson, Dana Farber Cancer Institute, Boston, USA
Genome Alterations in Human Lung Cancers
6.30 – 7.00 pm
1000 Genomes Project
Hans Lehrach, MPI for Molecular Genetics, Berlin, Germany
1000 Genomes Project – An integrated map of genetic variation
Hans Lehrach, MPI for Molecular Genetics, Berlin, Germany
1000 Genomes Project – An integrated map of genetic variation
7.00 pm
Supper
Wednesday, December 12,
2012
Symposium II: International Projects in Genome Research
9.00 – 9.30 am
John Blangero, Texas Biomedical Research Institute, San Antonio, USA
Identification of Complex Disease Genes Using Whole Genome Sequencing in Large Pedigrees
Identification of Complex Disease Genes Using Whole Genome Sequencing in Large Pedigrees
9.30 – 10.00 am
Joris A. Veltman, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
De novo diagnostics in patients with intellectual disability
De novo diagnostics in patients with intellectual disability
10.00 – 10.30 am
Alzheimer’s Disease Genetics Consortium (ADGC)
Gerard D. Schellenberg, University of Pennsylvania School of Medicine, Philadelphia, USA
Neurodegenerative disease genetics; GWAS, exomes and beyond
Gerard D. Schellenberg, University of Pennsylvania School of Medicine, Philadelphia, USA
Neurodegenerative disease genetics; GWAS, exomes and beyond
10.30 – 11.00 am
Coffee Break
11.00 – 11.30 am
International Human Epigenome Consortium (IHEC)
Peter Jones, USC Norris Comprehensive Cancer Center, Los Angeles, USA
The Cancer Epigenome
Peter Jones, USC Norris Comprehensive Cancer Center, Los Angeles, USA
The Cancer Epigenome
11.30 – 12.00 pm
International Human Epigenome Consortium (IHEC)
Jörn Walter, Saarland University, Germany
Control of DNA-methylation in development
Jörn Walter, Saarland University, Germany
Control of DNA-methylation in development
12.00 – 2.00 pm
Lunch Break and Poster Session I
12.00 - 01.00 pm odd numbers
01.00 - 02.00 pm even numbers
Company Satellite Sessions
Affymetrix UK Ltd
Caliper a PerkinElmer Company
Illumina UK Ltd
Bio-Rad Laboratories GmbH
2.00 – 2.30 pm
International Knockout Mouse Consortium / EUCOMM
Wolfgang Wurst, Helmholtz Zentrum Munich, Germany
International Mouse Knock-out Consortium: Resource to functionally validate all genes
Wolfgang Wurst, Helmholtz Zentrum Munich, Germany
International Mouse Knock-out Consortium: Resource to functionally validate all genes
2.30 – 3.00 pm
The International Mouse Phenotyping Consortium, EUMODIC and INFRAFRONTIER
Martin Hrabe de Angelis, Helmholtz Zentrum Munich, Germany
Creating a comprehensive encyclopedia of mammalian gene function
Martin Hrabe de Angelis, Helmholtz Zentrum Munich, Germany
Creating a comprehensive encyclopedia of mammalian gene function
3.00 – 3.30 pm
Matthias Mann, Max Planck Institute for Biochemistry, Munich, Germany
High resolution, quantitative mass spectrometry combines proteomics and genomics
High resolution, quantitative mass spectrometry combines proteomics and genomics
3.30 – 4.00 pm Coffee Break
Symposium III: Genomics of Common Disease I
4.00 – 4.15 pm
André Reis, University Erlangen-Nuremberg, Germany
Range of genetic mutations associated with severe non-syndromic sporadic intellectual disability: An exome sequencing study
Range of genetic mutations associated with severe non-syndromic sporadic intellectual disability: An exome sequencing study
4.15 – 4.30 pm
Vanessa Nieratschker, Central Institute for Mental Health, Mannheim, Germany
Pre-, peri- and postnatal stress in human and non-human off-spring: A convergent approach to study genetic and epigenetic impact on depression
Pre-, peri- and postnatal stress in human and non-human off-spring: A convergent approach to study genetic and epigenetic impact on depression
4.30 – 4.45 pm
Andre Franke, University Hospital Schleswig-Holstein, Kiel, Germany
Host-microbe interactions shape genetic risk for inflammatory bowel disease
Host-microbe interactions shape genetic risk for inflammatory bowel disease
4.45 - 5.00 pm
Robert Häsler, Christian Albrechts University of Kiel, Germany
Mapping the functional epigenome of Ulcerative Colitis in monozygotic twins
Mapping the functional epigenome of Ulcerative Colitis in monozygotic twins
5.00 - 5.30 pm
Coffee Break
5.30 - 5.45 pm
Anke Hinney, University of Duisburg-Essen, Germany
Childhood ADHD and obesity: Evidence for a common genetic link
Childhood ADHD and obesity: Evidence for a common genetic link
5.45 - 6.00 pm
Ralf Herwig, Max Planck Institute for Molecular Genetics, Berlin, Germany
An integrated catalogue of genome, methylome and gene expression variations in colon cancer
An integrated catalogue of genome, methylome and gene expression variations in colon cancer
Evening Lecture
6.00 - 7.00 pm
Randolph Nesse, The University of Michigan, Ann Arbor, USA
Evolutionary Medicine and Molecular Medicine: Synergistic Siblings
7.00 - 10.00 pm
Get-Together (Wine, Cheese, Live Music)
Thursday, December 13, 2012
Symposium IV: Genomics of Common Disease II
9.00 - 9.30 am
Keynote: Hugo A. Katus, Heidelberg University Hospital, Germany
Innovations in translational research – Successes of NGFN
Innovations in translational research – Successes of NGFN
9.30 - 9.45 am
Christina Loley, University of Lübeck, Germany
Association of X-chromosomal variants with coronary heart disease: Results from a meta-analysis
Association of X-chromosomal variants with coronary heart disease: Results from a meta-analysis
9.45 - 10.00 am
Martin Peifer, University of Cologne, Germany
Toward a novel genomics-based taxonomy of lung cancer: The Clinical Lung Cancer Genome Project
Toward a novel genomics-based taxonomy of lung cancer: The Clinical Lung Cancer Genome Project
10.00 - 10.15 am
Christel Herold-Mende, University of Heidelberg, Germany
Aberrant self-renewal and quiescence contribute to Glioblastoma aggressiveness
Aberrant self-renewal and quiescence contribute to Glioblastoma aggressiveness
10.15 - 10.45 am
Coffee Break
Symposium V: Functional Genomics
10.45 - 11.00 am
Jan Korbel, The European Molecular Biology Laboratory, Heidelberg, Germany
Genome sequencing of childhood medulloblastoma brain tumors links chromothripsis with TP53 mutations
Genome sequencing of childhood medulloblastoma brain tumors links chromothripsis with TP53 mutations
11.00 - 11.15 am
Gerrit Erdmann, German Cancer Research Center, Heidelberg, Germany
Secretion of Wnts is required for Wnt/ß-catenin pathway activity in colorectal cancer (CRC) despite APC or ß-catenin mutations
Secretion of Wnts is required for Wnt/ß-catenin pathway activity in colorectal cancer (CRC) despite APC or ß-catenin mutations
11.15 - 11.30 am
Sven Lindner, University Hospital Essen, Germany
LIN28B induces neuroblastoma and enhances MYCN levels via let-7 suppression
LIN28B induces neuroblastoma and enhances MYCN levels via let-7 suppression
11.30 - 11.45 am
Sören Westphal, University Clinic Ulm, Germany
Human BCL2-associated athanogene 3 (BAG3) mutations lead to dilated cardiomyopathy in zebrafish
Human BCL2-associated athanogene 3 (BAG3) mutations lead to dilated cardiomyopathy in zebrafish
11.45 - 12.00 pm
Zouhair Aherrahrou, University of Lübeck, Germany
Cyp17a1 deficient mice display increased body weight, visceral/subcutaneous fat deposition and altered lipid metabolism
Cyp17a1 deficient mice display increased body weight, visceral/subcutaneous fat deposition and altered lipid metabolism
12.00 - 2.00 pm
Lunch Break and Poster Session II
12.00 – 01.00 pm odd numbers
01.00 – 02.00 pm even numbers
Company Satellite Sessions
Life Technologies GmbH
Roche Diagnostics Deutschland GmbH
SEQUENOM GmbH
Nanostring Technologies, Inc.
2.00 – 2.15 pm
Ceremony: "Annemarie Poustka Poster Award 2012"
sponsored by Roche Diagnostics Deutschland GmbH
Christine Kuch, Roche Diagnostics Deutschland GmbH
Hugo A. Katus, Heidelberg University Clinics, Project Committee of NGFN?Plus / NGFN?Transfer in the Program of Medical Genome Research
sponsored by Roche Diagnostics Deutschland GmbH
Christine Kuch, Roche Diagnostics Deutschland GmbH
Hugo A. Katus, Heidelberg University Clinics, Project Committee of NGFN?Plus / NGFN?Transfer in the Program of Medical Genome Research
Symposium VI: Personalized Medicine
2.15 – 2.45 pm
Keynote: Rudi Balling, Luxembourg Centre for Systems Biomedicine, Luxembourg
Systems approaches to Parkinson´s disease
Systems approaches to Parkinson´s disease
2.45 - 3.00 pm
Nicole Teichmann, University Hospital rechts der Isar, Munich, Germany
A promising therapy strategy for PDAC: MEK1/2 inhibition with the novel chemotherapeutic drug BAY 86-9766 (RDEA119)
A promising therapy strategy for PDAC: MEK1/2 inhibition with the novel chemotherapeutic drug BAY 86-9766 (RDEA119)
3.00 – 3.15 pm
Margret Hoehe, Max Planck Institute for Molecular Genetics, Berlin, Germany
Haplotype-resolving multiple human genomes: Key to personalized medicine and genome biology
Haplotype-resolving multiple human genomes: Key to personalized medicine and genome biology
3.15 – 3.30 pm
Jeanette Erdmann, University of Lübeck, Germany
The risk of myoacardial infarction is increased by digenic mutation in GUCY1A3 and CCT7 - identified by exome sequencing in an extended family
The risk of myoacardial infarction is increased by digenic mutation in GUCY1A3 and CCT7 - identified by exome sequencing in an extended family
3.30 – 3.45 pm
Brajesh Kaistha, University of Marburg, Germany
High-throughput cell-based assays identify Placenta-specific 8 (Plac8; Onzin) as a key regulator of proliferation and survival in pancreatic cancer cells
High-throughput cell-based assays identify Placenta-specific 8 (Plac8; Onzin) as a key regulator of proliferation and survival in pancreatic cancer cells
3.45 – 4.00 pm
Concluding Remarks: Markus Nöthen, Friedrich-Wilhelms University, Bonn,
Speaker Project Committee of NGFN-Plus / NGFN-Transfer in the Program
of Medical Genome Research
4.00 - 4.30 pm
Closing Coffee
- Flyer (524.3KB)
- Abstract Book 2012 (3.3MB)
